Efficient Quercetin Sensor Utilizing Chitosan-Modified Carboxylated MWCNTs for Fast and Accurate Analysis

Abstract

A new electrochemical sensor incorporating a molecular imprinting polymer and multi-walled carbon nanotubes was successfully created for the sensitive detection of quercetin. The molecularly imprinted polymer was prepared by using quercetin as the template, 4-vinyl pyridine as the monomer, 2,2’-azobis (2-methylpropionitrile) as the initiator agent and ethylene glycol dimethacrylate as the cross-linker, respectively. A series of electrochemical experiments of title electrochemical sensor were investigated and the experimental results demonstrate that the sensor for quercetin demonstrates a broad detection range of 53 μM - 460.5 μM with low limit of detection of 0.11 μM. Additionally, this quercetin sensor exhibited long durable, and good replicable, and selective abilities in the presence of other interferents. Furthermore, this sensor was utilized for human serum sample to evaluate quercetin, and it exhibited satisfactory recovery results of 99.04 % - 103.85 %, indicating that the sensor has great potential in practical applications.

Supplementary files

Article information

Article type
Paper
Submitted
15 Mar 2025
Accepted
30 Jun 2025
First published
05 Jul 2025

React. Chem. Eng., 2025, Accepted Manuscript

Efficient Quercetin Sensor Utilizing Chitosan-Modified Carboxylated MWCNTs for Fast and Accurate Analysis

M. Duan, Y. Sun, X. Liu, S. Ma, Q. Li, H. Xu, C. Zhang, Q. Zhen and H. Pang, React. Chem. Eng., 2025, Accepted Manuscript , DOI: 10.1039/D5RE00121H

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