Amphiphilic coumarin derivatives have demonstrated potent antibiofilm activity against established methicillin-resistant Staphylococcus aureus (MRSA) biofilms. Scanning electron microscopy (SEM) revealed morphological changes to bacterial cells and eradication of extracellular matrix from established MRSA biofilms when treated with 7-benzyloxy coumarin derivatives.
S. O. Nitschke, M. Awad, A. G. Elliott, G. Lowe, C. Leigh, K. Neubauer, N. Thomas, S. M. Hickey and S. E. Plush, RSC Adv., 2025, 15, 25510 DOI: 10.1039/D5RA04358A
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