Investigating the potent antimicrobial properties of a supramolecular Zn(ii)-metallogel formed from an isophthalic acid-based low molecular weight gelator

Abstract

A zinc(II)-based metallogel was synthesized using isophthalic acid as a gelator in N,N-dimethylformamide at room temperature. The gel formation was confirmed by FT-IR spectroscopy, revealing coordination interactions responsible for network assembly. Rheological studies demonstrated the mechanical robustness and stability of the Zn(II)-metallogel under various conditions. Field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray (EDX) mapping analyses revealed a well-defined microstructure and uniform elemental distribution, providing insight into its morphology and composition. Antimicrobial evaluations showed notable inhibitory effects against both Gram-positive and Gram-negative bacterial strains, underlining the metallogel's broad-spectrum efficacy. These results indicate that the Zn(II)–isophthalic acid metallogel holds strong promise for applications in antimicrobial materials. Its structural integrity and bioactivity suggest potential utility in biomedical and industrial domains, promoting the development of advanced multifunctional materials.