Unified approach to synthesize diverse heterocyclics: a metal-free visible-light-promoted cyclization reaction to acquire sulfonylated spiro-trienones, coumarins and their derivatives

Abstract

Herein, a visible-light-promoted 9-thioxanthone-catalyzed cascade cyclization reaction to synthesize sulfonylated spiro-trienones, coumarins and their derivatives in yields of up to 98% under mild irradiation reaction conditions is reported. Furthermore, extensive studies, including gram-scale, radical capture, isotope and DFT experiments, were performed to gain insights into the possible reaction mechanism.