Issue 14, 2025, Issue in Progress

Five-membered heterocycles as promising platforms for molecular logic gate construction

Abstract

The field of molecular logic gates began thirty years ago with the early pioneers de Silva et al. (A. P. de Silva, H. Q. N. Gunaratne and C. P. McCoy, Nature, 1993, 364, 42) laying the foundation for modern molecular-scale switches and devices. Recent reports of lab-on-a-molecule and molecular calculators (Moleculators) demonstrate the potential of this bottom-up approach. Five-membered heterocycles were central to the first reported logic gates in 1994 and remain valuable scaffolds in the present day. This review provides an overview of logic gate design using Boolean logic, introduces the work of the first pioneers, and highlights recently reported five-membered heterocycle logic gates.

Graphical abstract: Five-membered heterocycles as promising platforms for molecular logic gate construction

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Article information

Article type
Review Article
Submitted
01 Feb 2025
Accepted
28 Mar 2025
First published
04 Apr 2025
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2025,15, 10565-10572

Five-membered heterocycles as promising platforms for molecular logic gate construction

A. Ciupa, RSC Adv., 2025, 15, 10565 DOI: 10.1039/D5RA00749F

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