Photocatalyzed defluorinative allylsulfonylation of alkynes to access gem-difluorinated sulfonyl-1,4-dienes

Abstract

A photo-catalyzed three-component gem-difluoroallylsulfonylation of alkynes with trifluoromethyl alkenes and sodium sulfinates via selective C–F bond activation has been described. This metal-free allylsulfonylation provides an efficient strategy for the stereospecific synthesis of gem-difluorinated sulfonyl-1,4-dienes under mild conditions.