Carbamoylation of azaarenes and olefins with formamides through dual photoredox/HAT catalysis

Abstract

A unique strategy for the photoinduced Minisci and Giese carbamoylation with readily available formamides is described. This approach avoids using less atom-efficient carbamoyl precursors (e.g., oxamic acids) and sacrificial oxidants, relying on dual photoredox/hydrogen atom transfer (HAT) catalysis. The synthetic value of the carboxamide functionality was illustrated with different straightforward transformations that gave access to diverse azaarene derivatives.