Synthesis of pyrrolo[1,2-a]quinoxalines via an electrochemical C(sp3)–H functionalization

Abstract

An efficient iodine-mediated electrochemical C(sp³)–H cyclization under mild conditions was developed. A variety of functionalized quinoxalines can be obtained with good to excellent yields by virtue of this method. The reaction was found to feature a broad substrate scope, regulation of product distribution, scalable preparation and high atom economy. The reaction mechanism was investigated in detail.