Visible-light-induced Photochemical Synthesis of Spirooxindoles Comprising Carbocyclic Scaffolds

Abstract

Notwithstanding the notable development achieved in the asymmetric and photochemical construction of spirooxindoles comprising heterocyclic compounds, constructing spirooxindoles containing carbocyclic compounds has not been extensively explored. Drawing inspiration from the incredible structural landscape and pharmaceutical activities associated with spirooxindoles, the synthesis of spirooxindoles comprising carbocyclic compounds to provide unique reactivity and activity is highly desirable. This mini-review article aims to give a brief outline of the visible-light-induced photochemical approaches established over the last decades for accessing spirooxindoles, comprising different ring-size carbocyclic scaffolds. Beyond outlining the development achieved to date, we have emphasized the reaction mechanism and highlighted the limitations associated with the reactions, providing insights for future advancement.