H₂SO₄-Catalyzed One-Step Synthesis of β,β′-Carbon-Bridged bisBODIPYs from BODIPYs and Aldehydes

Abstract

An H2SO4-promoted condensation reaction between BODIPYs and aldehydes has been established, enabling a straightforward and versatile approach for the highly regioselectivity synthesis of β,β′-carbon-bridged bisBODIPYs. This one pot method efficiently facilitates the condensation of a range of aldehydes, including aromatic, heteroaromatic, and aliphatic derivatives to deliver the corresponding target products. Importantly, by eliminating multi step procedures and circumventing the manipulation of labile intermediates, this approach significantly streamlines the synthetic process.