3H-Phenothiazin-3-one: A Photocatalyst for the Mild Oxidation of Boronic Acids Under Green LED Irradiation

Abstract

3H-Phenothiazin-3-one is a small organic molecule with established biological properties, yet its potential as an organic photocatalyst remains largely unexplored. Herein, we report a green and efficient aerobic oxidation of boronic acids employing 3H-phenothiazin-3-one as the photocatalyst. The transformation proceeds under mild conditions, using green LED irradiation and atmospheric oxygen as the terminal oxidant. A broad range of boronic acids was successfully converted to the corresponding hydroxy derivatives, showcasing the excellent functional-group tolerance and synthetic utility of the developed photochemical protocol. Preliminary mechanistic investigations were undertaken to elucidate the reaction pathway and to identify the reactive oxygen species involved.