Selenium Dioxide-Mediated Oxidative Annulation of Sufonyl o-Hydroxyacetophenones with Acetophenones. One-pot Synthesis of Aurone Analogs

Abstract

Selenium dioxide-mediated one-pot oxidative annulation of sulfonyl o-hydroxyacetophenones with acetophenones generates good yields of aurone analogs in refluxing dioxane under the dry air atmosphere conditions. A plausible mechanism is proposed and discussed here. In the overall reaction process, selenium-containing compounds were generated as the byproducts. Various oxidants-promoted conditions were also investigated for one-pot annulation.