A carrier-free nano-photosensitizer for red light-activated NO release and combination therapy

Abstract

In this work, a multifunctional nanoparticles (A-PIB NPs) constructed by a nitric oxide (NO) donor L-arginine and the boron dipyrromethene was used for red light-responsive and spatiotemporally-controllable NO release. A-PIB NPs could produce singlet oxygen and NO under 630 nm light irradiation, achieving controlled release of NO and being used for combination therapy of tumors.

Supplementary files

Article information

Article type
Communication
Submitted
10 Jun 2025
Accepted
12 Aug 2025
First published
12 Aug 2025

Org. Biomol. Chem., 2025, Accepted Manuscript

A carrier-free nano-photosensitizer for red light-activated NO release and combination therapy

C. Li, H. Qi, J. Jia, Q. Lin and W. Lin, Org. Biomol. Chem., 2025, Accepted Manuscript , DOI: 10.1039/D5OB00959F

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