A carrier-free nano-photosensitizer for red light-activated NO release and combination therapy
Abstract
In this work, a multifunctional nanoparticles (A-PIB NPs) constructed by a nitric oxide (NO) donor L-arginine and the boron dipyrromethene was used for red light-responsive and spatiotemporally-controllable NO release. A-PIB NPs could produce singlet oxygen and NO under 630 nm light irradiation, achieving controlled release of NO and being used for combination therapy of tumors.