Issue 28, 2025
From the journal:

Organic & Biomolecular Chemistry

Dual photoredox/palladium-catalyzed three-component reaction for the synthesis of trifluoromethylated allylic alcohols†

Xiao-Lin Wang,‡a   Kavuri Rupa,a   Sheng-Cai Zheng ORCID logo *a  and  Xiaoming Zhao ORCID logo *a  

* Corresponding authors

a School of Chemical Technology and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, P.R. China
E-mail: zhengsc@tongji.edu.cn, xmzhao08@mail.tongji.edu.cn

Abstract

An effective three-component reaction using simple and easily obtained cyclic vinyl carbonates, olefins and CF3SO2Na under dual photoredox/palladium catalysis was documented for the synthesis of trifluoromethylated allylic alcohols bearing quaternary carbon centers with high stereoselectivity.

Graphical abstract: Dual photoredox/palladium-catalyzed three-component reaction for the synthesis of trifluoromethylated allylic alcohols

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D5OB00926J
Article type
Communication
Submitted
05 Jun 2025
Accepted
21 Jun 2025
First published
23 Jun 2025

Org. Biomol. Chem., 2025,23, 6687-6693

Permissions

Request permissions

Dual photoredox/palladium-catalyzed three-component reaction for the synthesis of trifluoromethylated allylic alcohols

X. Wang, K. Rupa, S. Zheng and X. Zhao, Org. Biomol. Chem., 2025, 23, 6687 DOI: 10.1039/D5OB00926J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements