Efficient photocatalytic synthesis of benzylhydrazine

Abstract

In this paper, an efficient synthesis of benzylhydrazine derivatives from unactivated phenylethanol analogues was successfully developed under mild redox-neutral reaction conditions. At the same time, it was also proved that a wide range of phenylethanol analogues and azodicarboxylates can be successfully applied in this fragment coupling transformation. Moreover, this method can be applied to the synthesis of active molecules of isocarboxazid.