An electrochemical method for sunitinib synthesis was developed using iodide as a mediator, enabling sustainable amidation (72% yield) and condensation (95% yield) at room temperature. This study highlights iodide's crucial role in the reaction mechanism and the potential of graphite electrodes as eco-friendly alternatives to conventional synthetic methods.
A. Alni, R. G. Mahardika, A. Danova and E. Hermawati, Org. Biomol. Chem., 2025, Advance Article , DOI: 10.1039/D5OB00377F
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