Kinetic resolution of binols and biphenols via dehydrogenative coupling with hydrosilanes catalyzed by chiral FLPs

Abstract

A kinetic resolution of binols and biphenols has been realized via dehydrogenative coupling with hydrosilanes catalyzed by a frustrated Lewis pair of chiral borane and chiral phosphine. A variety of axially chiral siloxanes, along with the corresponding optically active binols and biphenols, were obtained in good yields with moderate to high enantioselectivities.