Hetero-Diels–Alder reactions of (isobenzo)furans

Abstract

Hetero-Diels–Alder reactions of furans and isobenzofurans provide convergent redox-neutral access to hetero-oxanorbornene derivatives. These versatile intermediates serve as precursors to a variety of heterocycles, polymers, and complex natural products. Herein we comprehensively review this area of research and speculate on what developments are required to advance the field.

Graphical abstract: Hetero-Diels–Alder reactions of (isobenzo)furans

Article information

Article type
Review Article
Submitted
11 Jan 2025
Accepted
07 Feb 2025
First published
14 Feb 2025
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2025, Advance Article

Hetero-Diels–Alder reactions of (isobenzo)furans

C. J. DeAngelis and C. G. Newton, Org. Biomol. Chem., 2025, Advance Article , DOI: 10.1039/D5OB00050E

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