Stereoselective addition of phenols to 2-chloroprop-2-ene-1-sulfonyl fluoride (CESF) for the synthesis of a class of novel vinyl sulfonyl fluorides

Abstract

Herein, we describe a novel and rapid method for synthesizing vinyl ethers. This metal-free, straightforward technique efficiently introduces the vinyl ether moiety along with the sulfonyl fluoride functional group under mild conditions within 10 minutes. The strategy demonstrates high efficiency across various substrates, enabling the rapid synthesis of structurally diverse compounds. This approach highlights the potential to revolutionize industrial chemical processes by providing a practical and efficient route for organic synthesis.