A non-enzymatic glucose sensor based on nanoflower-like Ni–MoS2/CuCo2O4

Abstract

Excessive glucose content in beverages poses potential health risks, highlighting the need for highly sensitive detection methods. In this study, a novel nanoflower-like Ni–MoS₂/CuCo₂O₄ composite was synthesized and optimized for glucose detection in beverages. The structural characterization, compositional optimization, and performance evaluation of the prepared Ni–MoS₂/CuCo₂O₄ material were systematically conducted. The optimized sensor exhibited exceptional sensitivity, achieving 1102 μA mmol⁻¹ cm⁻² within a broad detection range of 0.5–293.0 μmol L⁻¹, along with a low detection limit of 0.5 μmol L⁻¹. Cyclic stability testing demonstrated that the Ni–MoS₂/CuCo₂O₄/GCE electrode maintained excellent stability and a high recovery rate over 14 consecutive days, with a relative standard deviation (RSD) of 5.92%. Furthermore, glucose detection in real beverage samples yielded an RSD of less than 6%, confirming the sensor's reliability and accuracy. This study offers a novel approach for developing highly sensitive glucose sensors with low detection limits.