Synthetic methodologies of Nanohybrids Gold Nanorod@MOF focused on biological applications

Abstract

A stable and controllable coating on the surface of gold nanorods (AuNRs) can be formed by using metal-organic frameworks (MOFs), allowing to avoid agglomeration of the nanohybrid AuNR@MOF and also expanding the functionality of the plasmon nanoparticles. In this review, we discuss the chemical role of the different components of the nanohybrid, i.e., AuNR, surface ligand or mesoporous nanostructure (MN) and the MOF around the AuNR. The methodologies used in the different synthesis stages and the factors to be considered to maintain stability in the construction of this type of nanostructures are also reported. Furthermore, we observed that there are a wide variety of MOF morphologies that can be built around AuNRs, even using the same components for its formation, which varies depending on the synthesis methodology. Finally, we discuss about the broad range of applications, mainly biologicals, that possess the AuNR@MOF nanohybrids.