Issue 27, 2025

Aerobic oxidative synthesis of o-phenylenediamines from cyclohexanones

Abstract

A novel iodine and copper co-catalyzed method for the direct conversion of cyclohexanones into substituted o-phenylenediamines has been developed. This transformation is notable for its compatibility with a variety of amines and because it utilizes air as a green oxidant under mild conditions.

Graphical abstract: Aerobic oxidative synthesis of o-phenylenediamines from cyclohexanones

Supplementary files

Article information

Article type
Communication
Submitted
10 Apr 2025
Accepted
07 Jun 2025
First published
13 Jun 2025

Green Chem., 2025,27, 8120-8125

Aerobic oxidative synthesis of o-phenylenediamines from cyclohexanones

Y. Sun, S. Tang, B. Zhao and N. Jiao, Green Chem., 2025, 27, 8120 DOI: 10.1039/D5GC01786F

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