Efficient continuous flow oxidation of furfural to maleic anhydride using O2 as a green oxidant

Abstract

This research investigates different oxidative pathways to obtain maleic anhydride starting from the biorenewable furfural in continuous flow. A single step O₂¹ oxidation towards maleic anhydride was investigated but found to lack selectivity. Nonetheless, the resulting product analysis provided valuable insight into the possible reaction mechanism, uncovering an interesting solvent effect. Building on this, an existing slow reacting two-step pathway was translated towards a continuous one, achieving a fast and highly productive conversion towards maleic anhydride while aligning with green chemistry principles.