A straightforward approach to robust thiazolylidene gold complexes: efficient catalysts for propargylamide cycloisomerizations

Abstract

The straightforward synthesis of new thiazolylidene gold complexes is described. Despite their decreased steric protection, these complexes demonstrate excellent stability and high catalytic activity in the HFIP-assisted cycloisomerization of propargylamides. The synthesis and catalytic activity of a novel, stable thiazolylidene gold alkoxide complex is also reported.