Keto-enol at play: Regioisomerism Regulated Switching in Indole-Naphthyl Schiff Bases

Abstract

Indole-naphthyl Schiff bases studied in this work show the importance of hydroxyl positions on enol (E)-keto (K) emissions, aggregation-induced (AIE), and viscosity-dependent emission properties. Single-crystal X-ray diffraction and computational studies provide insights into the structural properties of the tautomeric species. INpOH-1 and INpOH-2 demonstrated potential for distinguishing normal and cancer cells based on their polarity and viscosity sensitivity.

Supplementary files

Article information

Article type
Paper
Submitted
23 May 2025
Accepted
28 Aug 2025
First published
30 Aug 2025

Phys. Chem. Chem. Phys., 2025, Accepted Manuscript

Keto-enol at play: Regioisomerism Regulated Switching in Indole-Naphthyl Schiff Bases

S. Choudhary, A. K. Shukla, S. Panyala, A. Mahale, P. Vipparthi, O. P. Kulkarni and A. Bhattacharya, Phys. Chem. Chem. Phys., 2025, Accepted Manuscript , DOI: 10.1039/D5CP01939G

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