Luminescent array sensors for pathogen identification using AIE-active cationic iridium complexes

Abstract

Five luminescent AIE-active iridium(III) probes were employed for rapid and specific identification of an antibiotic-sensitive and -resistant pathogenic strains, including ESKAPE bacteria, achieving nearly 100% accuracy even at low concentration of 105 CFU/mL. This sensor array demonstrated significant potential for identification and quantitative detection of mixed infection in urine of clinically relevant bacteria linked to urinary tract infections (UTI).