Sulfonium salt-mediated phosphorodithioation of alkynes with P4S10 and alcohols to access Z-vinyl phosphorodithioates

Abstract

In this work, we report a practical and convenient sulfonium salt-mediated alkyne difunctionalization reaction. This method uses inexpensive P₄S₁₀ as both the sulfur and phosphorus sources, providing an efficient approach for access to various Z-vinyl phosphorodithioates. Preliminary studies suggest that the reaction undergoes a nucleophilic addition to in situ generated alkynyl sulfonium salts and subsequently a demethylation process.