From the journal:

Chemical Communications

Enhanced-sensitivity profiling of natural products from TLC plates using a facile graphite-based LA-DART-MS platform

Xingyu Wang,a   Jianxing Lv,a   Yilin Chen,a   Liying You,a   Linnan Li, ORCID logo *a   Zhengtao Wanga  and  Li Yang*a  

* Corresponding authors

a State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China
E-mail: linnanli@shutcm.edu.cn, yl7@shutcm.edu.cn

Abstract

A graphite-assisted technique was used to enhance laser-assisted ionization TLC direct analysis in real time mass spectrometry (LA-TLC-DART-MS), improving the signal responses for flavonoids, alkaloids, volatile oils, and organic acids. When applied to citrus herbs, this method identified 14 compounds and differentiated samples from different origins, demonstrating its potential for natural product quality control.

Graphical abstract: Enhanced-sensitivity profiling of natural products from TLC plates using a facile graphite-based LA-DART-MS platform

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D5CC04369G
Article type
Communication
Submitted
31 Jul 2025
Accepted
25 Nov 2025
First published
26 Nov 2025

Chem. Commun., 2025, Advance Article

Permissions

Request permissions

Enhanced-sensitivity profiling of natural products from TLC plates using a facile graphite-based LA-DART-MS platform

X. Wang, J. Lv, Y. Chen, L. You, L. Li, Z. Wang and L. Yang, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC04369G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements