From the journal:

Chemical Communications

ROS-responsive SERS probes for real-time monitoring of oxidative stress in traumatic brain injury†

Dianqi Zhang,‡ab   Li Zhou,‡ab   Zhun Nie,‡ab   Wei Zhang,ab   Fabiao Yu ORCID logo *ab  and  Rui Wang*ab  

* Corresponding authors

a Key Laboratory of Emergency and Trauma, Ministry of Education, Key Laboratory of Hainan Trauma and Disaster Rescue, Key Laboratory of Haikou Trauma, The First Affiliated Hospital of Hainan Medical University, Hainan Medical University, Haikou 571199, China
E-mail: yufabiao@muhn.edu.cn, wangrui@muhn.edu.cn

b Engineering Research Center for Hainan Bio-Smart Materials and Bio-Medical Devices, Key Laboratory of Hainan Functional Materials and Molecular Imaging, College of Emergency and Trauma, Hainan Medical University, Haikou 571199, China

Abstract

We report a ROS-responsive SERS probe enabling real-time, spatiotemporal monitoring of oxidative stress in traumatic brain injury. The probe offers highly sensitive and biocompatible detection in living bEnd.3 cells and mice models, providing a powerful tool for dynamic redox analysis in biological systems.

Graphical abstract: ROS-responsive SERS probes for real-time monitoring of oxidative stress in traumatic brain injury

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Article information

DOI
https://doi.org/10.1039/D5CC03052H
Article type
Communication
Submitted
03 Jun 2025
Accepted
12 Jul 2025
First published
15 Jul 2025

Chem. Commun., 2025, Advance Article

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ROS-responsive SERS probes for real-time monitoring of oxidative stress in traumatic brain injury

D. Zhang, L. Zhou, Z. Nie, W. Zhang, F. Yu and R. Wang, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC03052H

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