One-pot electrochemical synthesis of N-trifluoromethylthio sulfoximines from sulfoximines via N-SCN intermediates

Abstract

We reported an electrochemical method for the generation of N-thiocyanato sulfoximines from sulfoximines and ammonium thiocyanate. With NH₄I as the mediator and electrolyte, the presynthesis of N–Br sulfoximines was avoided. Moreover, this sustainable approach can be applied in the synthesis of N-trifluoromethylthio sulfoximines in one pot by varying the sulfoximines.