One-pot electrochemical synthesis of N-trifluoromethylthio sulfoximines from sulfoximines via N-SCN intermediates

Abstract

We reported an electrochemical method for the generation of N-thiocyanato sulfoximines from sulfoximines and ammonium thiocyanate. With NH4I as the mediator and electrolyte, the presynthesis of N-Br sulfoximines were avoided. Moreover, this sustainable approach can be applied in the synthesis of N-trifluoromethylthio sulfoximines by varying sulfoximines in one pot.

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Article information

Article type
Communication
Submitted
29 May 2025
Accepted
10 Jul 2025
First published
11 Jul 2025

Chem. Commun., 2025, Accepted Manuscript

One-pot electrochemical synthesis of N-trifluoromethylthio sulfoximines from sulfoximines via N-SCN intermediates

P. Qian, Q. Meng, T. Sheng, H. Niu, W. Zhan, L. Zhang and D. Zheng, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC03026A

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