One-pot electrochemical synthesis of N-trifluoromethylthio sulfoximines from sulfoximines via N-SCN intermediates†
Abstract
We reported an electrochemical method for the generation of N-thiocyanato sulfoximines from sulfoximines and ammonium thiocyanate. With NH4I as the mediator and electrolyte, the presynthesis of N–Br sulfoximines was avoided. Moreover, this sustainable approach can be applied in the synthesis of N-trifluoromethylthio sulfoximines in one pot by varying the sulfoximines.