Cu2+-activatable fluorescence and chemiluminescence dual-mode sensing platform for visual detection of thiram

Pan Zhu; Yuanyu Tang; Yu Tang; Yating Xu; Shaojing Zhao; Chaoyi Yao; Benhua Wang; Xiangzhi Song; Minhuan Lan

doi:10.1039/D5CC03008K

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Cu²⁺-activatable fluorescence and chemiluminescence dual-mode sensing platform for visual detection of thiram†

Pan Zhu,^a Yuanyu Tang,^a Yu Tang,^b Yating Xu,^a Shaojing Zhao,^a Chaoyi Yao,^a Benhua Wang,

^a Xiangzhi Song

^a and Minhuan Lan

*^a

Author affiliations

* Corresponding authors

^a College of Chemistry and Chemical Engineering, Central South University, Changsha, P. R. China
E-mail: minhuanlan@csu.edu.cn

^b Department of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, P. R. China

Abstract

Herein, we developed a Cu²⁺-activatable dual-mode fluorescence and chemiluminescence probe (Ac-Do-Py) for thiram detection via competitive binding, achieving a detection limit of 100 nM under chemiluminescence mode. This first portable platform with dual fluorescence/chemiluminescence responses enables in situ monitoring of thiram residues on fruit surfaces.

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Article information

DOI: https://doi.org/10.1039/D5CC03008K
Article type: Communication
Submitted: 28 May 2025
Accepted: 28 Jun 2025
First published: 03 Jul 2025

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Chem. Commun., 2025,61, 11657-11660

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Cu²⁺-activatable fluorescence and chemiluminescence dual-mode sensing platform for visual detection of thiram

P. Zhu, Y. Tang, Y. Tang, Y. Xu, S. Zhao, C. Yao, B. Wang, X. Song and M. Lan, Chem. Commun., 2025, 61, 11657 DOI: 10.1039/D5CC03008K

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Chemical Communications