From the journal:

Chemical Communications

Simultaneous detection of nitroreductase and adenosine triphosphate using a dual-emission fluorescent probe†

Yumei Xu, ORCID logo *a   Fang Nian,a   Jinmei Wei,b   Li Li,a   Runtian Ma, ORCID logo a   Sudai Maa  and  Wenting Wang*c  

* Corresponding authors

a Institute of Agricultural Resources Chemistry and Application, College of Science, Gansu Agriculture University, No. 1 Yingmen village, Anning District, Lanzhou, Gansu 730070, China
E-mail: xuym@gsau.edu.cn

b State Key Laboratory of Aridland Crop Science, Gansu Agricultural University, Lanzhou 730070, China

c College of Life and Health, Wuhan Vocational College of Software and Engineering, Wuhan 430205, China

Abstract

Herein, we developed a novel dual-emission fluorescent probe DFP, for the simultaneous detection of adenosine triphosphate (ATP) and nitroreductase (NTR) in living cells. This innovative dual-channel fluorescence detection approach facilitated parallel spatial mapping of NTR and ATP distributions, providing insights into the interplay between energy metabolism and redox homeostasis.

Graphical abstract: Simultaneous detection of nitroreductase and adenosine triphosphate using a dual-emission fluorescent probe

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Article information

DOI
https://doi.org/10.1039/D5CC02820E
Article type
Communication
Submitted
22 May 2025
Accepted
18 Jul 2025
First published
06 Aug 2025

Chem. Commun., 2025, Advance Article

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Simultaneous detection of nitroreductase and adenosine triphosphate using a dual-emission fluorescent probe

Y. Xu, F. Nian, J. Wei, L. Li, R. Ma, S. Ma and W. Wang, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC02820E

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