From the journal:

Chemical Communications

Smartphone-assisted tuberculosis detection by a smart amplification process and lateral flow immunoassay with a 3D-printed device†

Chung-An Chen, ORCID logo ab   Natalie Yi-Ju Ho,b   Chang-Chi Yang,b   Hui-Yi Hsiao, ORCID logo c   Tse-Hao Huang,b   Ming-Kai Hsieh,ab   Po-Liang Lai*ab  and  Tsung-Ting Tsai ORCID logo *ab  

* Corresponding authors

a School of Medicine, Chang Gung University, Taoyuan, Taiwan
E-mail: tsai1129@gap.cgu.edu.tw

b Department of Orthopaedic Surgery, Spine Section and Bone and Joint Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan

c Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan

Abstract

A portably 3D-printed sensing platform combining a sunrise-biotin-labeled smart amplification process (sb-SmartAmp) and stacking pad lateral flow immunoassay (sLFIA) enables smartphone-assisted image analysis or naked-eye detection for on-site TB diagnosis, validated with clinical TB samples beyond in vitro testing.

Graphical abstract: Smartphone-assisted tuberculosis detection by a smart amplification process and lateral flow immunoassay with a 3D-printed device

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Article information

DOI
https://doi.org/10.1039/D5CC02403J
Article type
Communication
Submitted
29 Apr 2025
Accepted
20 Jul 2025
First published
22 Jul 2025

Chem. Commun., 2025, Advance Article

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Smartphone-assisted tuberculosis detection by a smart amplification process and lateral flow immunoassay with a 3D-printed device

C. Chen, N. Y. Ho, C. Yang, H. Hsiao, T. Huang, M. Hsieh, P. Lai and T. Tsai, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC02403J

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