C–H functionalisation of [2.2]paracyclophane under copper catalysis

Kun Zhou; Rui-Rui Wu; Xin-Rou Zhong; Jun Pu; Xin Yang; Kai Liu; Yue Wang; Dan-Qian Xu; Shao-Jie Lou

doi:10.1039/D5CC02283E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

C–H functionalisation of [2.2]paracyclophane under copper catalysis†

Kun Zhou,*^a Rui-Rui Wu,^a Xin-Rou Zhong,^a Jun Pu,

^a Xin Yang,^a Kai Liu,^a Yue Wang,^a Dan-Qian Xu

*^a and Shao-Jie Lou

*^a

Author affiliations

* Corresponding authors

^a Catalytic Hydrogenation Research Center, State Key Laboratory of Green Chemical Synthesis and Conversion, Key Laboratory of Green Pesticides and Cleaner Production Technology of Zhejiang Province, Zhejiang University of Technology, Hangzhou 310014, P. R. China
E-mail: chrc@zjut.edu.cn, loushaojie@zjut.edu.cn

Abstract

The direct C–H functionalisation of [2.2]paracyclophane (PCP) by forging diverse C–C bonds is appealing, yet has remained underexplored. Herein, we describe a copper-catalysed non-directed C–H arylation and alkenylation of PCP with various iodonium salts. This method features high selectivity, broad substrate scope, and mild conditions, constituting a practical platform for modular access to PCP derivatives.

Download options Please wait...

Supplementary files

Supplementary information PDF (8050K)

Article information

DOI: https://doi.org/10.1039/D5CC02283E
Article type: Communication
Submitted: 24 Apr 2025
Accepted: 26 Jun 2025
First published: 27 Jun 2025

Download Citation

Chem. Commun., 2025, Advance Article

Permissions

Request permissions

C–H functionalisation of [2.2]paracyclophane under copper catalysis

K. Zhou, R. Wu, X. Zhong, J. Pu, X. Yang, K. Liu, Y. Wang, D. Xu and S. Lou, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC02283E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Chemical Communications

C–H functionalisation of [2.2]paracyclophane under copper catalysis†

Abstract

Supplementary files

Article information

Download Citation

Permissions

C–H functionalisation of [2.2]paracyclophane under copper catalysis

Social activity

Search articles by author

Spotlight

Advertisements