Electrochemical C–H functionalization reaction of N-heterocycles with alkyl iodides

Abstract

Herein, we report on an electrochemical protocol for the C–H alkylation of N-heterocycles with easily accessible alkyl halides. A wide range of azauracil derivatives including bioactive tethered azauracil, pyrazinone and quinoxalinone were well accommodated and delivered the alkylated products in good to excellent yield.