Exclusive macrocyclization through multiple Si–O bond formations from diol and dichlorosilane

Abstract

This paper describes an exceptionally efficient macrocyclization method through multiple Si–O bond formations between diol and dichlorosilane. The square-shaped cyclic tetramer was exclusively obtained due to a hemilabile conformational lock of Ar–O–Si–O–Ar linkage. The synthetic method is significantly efficient, rapid, and feasible even under high concentration.