Issue 34, 2025

Pd-catalyzed imine synthesis from nitroarenes via Fe–H2O under electromagnetic milling

Abstract

This article introduces a novel, eco-friendly, one-pot method for synthesizing imines via mechanochemistry. Using water as a hydrogen donor and iron as a reducing agent, nitroaromatics react with aldehydes in the presence of a palladium catalyst to form imines efficiently.

Graphical abstract: Pd-catalyzed imine synthesis from nitroarenes via Fe–H2O under electromagnetic milling

Supplementary files

Article information

Article type
Communication
Submitted
26 Jan 2025
Accepted
24 Mar 2025
First published
24 Mar 2025

Chem. Commun., 2025,61, 6316-6319

Pd-catalyzed imine synthesis from nitroarenes via Fe–H2O under electromagnetic milling

X. Lu, F. Zhang, F. Yan, Q. Liu, Y. Zhao, M. Du, L. Zhang, X. Li, Z. Zhao and H. Liu, Chem. Commun., 2025, 61, 6316 DOI: 10.1039/D5CC00498E

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