Here, a supramolecular strategy that relies on the G-quadruplex DNA recognition-driven disaggregation of pentamethylene cyanine Cy5-ph-H aggregates is outlined，which can turn on its fluorescence and be used to visualize G-quadruplex DNA in living cells and highly target to mitochondria.
L. Guan, J. li, Y. Zhou, A. Li, L. Yin, W. Guan and Y. Fu, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC00436E
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