Ru(ii)-catalyzed oxidative (4+3) C–H/C–H annulation of 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones with allyl alcohol

Abstract

A ruthenium(II)-catalyzed direct oxidative (4+3) C–H/C–H annulation of 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones with allyl alcohol has been described. The developed method yielded the corresponding annulated products in moderate to good yields. In addition, based on the control experimental results, a possible reaction mechanism has been proposed for the (4+3) C–H/C–H annulation reaction.