DNDMH enabled C(sp3)–H nitration of aryl alkenes†
Abstract
C(sp3)–H bond nitration provides facile access to nitro compounds that are inaccessible through traditional nitration pathways. This work describes a C(sp3)–H bond nitration of aryl alkenes using DNDMH, a nitration reagent developed previously in our lab. Notably, this novel nitration process presents excellent regioselectivity and chemoselectivity between C(sp3)–H nitration and C(sp2)–H nitration.