Visualizing ozone fluctuations employing a fluorescent probe in stimulated-epilepsy cell models

Abstract

BID-Ozo, a mitochondrial-targeted fluorescence probe specifically designed to detect endogenous ozone (O₃) was developed. A significant increase in intracellular O₃ was observed in PC12 cells stimulated with high concentrations of glutamate (Glu), which is used to model epilepsy.

Supplementary files

Article information

Article type
Communication
Submitted
11 Dec 2024
Accepted
24 Apr 2025
First published
28 Apr 2025

Chem. Commun., 2025, Accepted Manuscript

Visualizing ozone fluctuations employing a fluorescent probe in stimulated-epilepsy cell models

J. Zhang, Y. Duan, C. Liu, M. Zhang, H. Liu, X. Ming, Y. Li, X. Jiao, X. Wang and B. Tang, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D4CC06310D

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