Issue 21, 2025

Construction of a colorimetric glyphosate detection platform based on peroxidase-like activity of MOF-818(Cu)

Abstract

To develop a simple, rapid, and low-cost detection method for the field detection of glyphosate, we developed a “signal-off” detection system for glyphosate residues, using the peroxidase (POD)-like activity of a metal–organic framework (MOF-818) and catalytic inhibition induced by glyphosate. Experimental results demonstrated this detection platform exhibited a linear range from 2 μM to 100 μM (R2 = 0.99) with a low detection limit (LOD) of 1 μM. And it showed excellent anti-interference performance even in the complex interfering ions. In addition, the relative standard deviations (RSD) of three environmental water samples with varying pollution levels were all below 9%, demonstrating the method reliability in practical applications.

Graphical abstract: Construction of a colorimetric glyphosate detection platform based on peroxidase-like activity of MOF-818(Cu)

Supplementary files

Article information

Article type
Paper
Submitted
18 Mar 2025
Accepted
06 May 2025
First published
07 May 2025

Anal. Methods, 2025,17, 4424-4431

Construction of a colorimetric glyphosate detection platform based on peroxidase-like activity of MOF-818(Cu)

K. Zhang, X. Ding, X. Zhang, J. Luan, Q. Guo, J. Zheng and N. Wang, Anal. Methods, 2025, 17, 4424 DOI: 10.1039/D5AY00449G

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