Development of a Fully Paper-Based Device for Quantitative Detection of Digoxin at the Point of Care
Abstract
We are the first to integrate H2O2 degradation and gold nanorod (GNR) etching on paper with the lateral-flow immunoassay (LFA) in a 3D-printed device to achieve semi-quantitative results for therapeutic drug monitoring of digoxin by correlating different color outputs to different digoxin concentrations.