Rapid and Sensitive Detection of Dextran Sulfate based on an Ionic Liquids-based Turn-on Micro-optode

Abstract

A comprehensive fluorometric method has been developed to detect dextran sulfate sodium salt (DSS) utilizing next-generation fluorescent ionic liquids (ILs)-based fluorescent micro-optode, nHPTIL outperforming other biomacromolecules having detection and quantification limits in the ng/mL range in aqueous media. A handy paper-based test kit experiment was also explored for the detection of DSS without using a costly instrumental technique. The present report not only enables the rapid and visual detection of DSS, but also facilitates the broader utilization of ILs-based photonic materials for the fabrication of next-generation photoluminescent low-dimensional optodes for biomedical applications, disease diagnosis, environmental monitoring, and forensic security.