Laser wavelength selection in Raman spectroscopy

Abstract

Research in Raman spectroscopy continues to abound in a diverse range of application spaces and concurrently, components of Raman systems have become increasingly sophisticated. Laser wavelength choice is a key question in any Raman spectroscopy experiment, and the wavelength required, or indeed wavelengths, depends on a number of factors. For instance, are trace compounds being interrogated and thus plasmonic enhancement required? Or, are the experiments targeted at a specific molecule, or class of analytes, which are resonant at a specific wavelength range? Safety, resolution, and ease of post-processing spectra, can also be crucial in the decision process. While laser vendors commonly offer guidance in terms of what to consider when picking lasers for Raman studies, advice tends to be succinct. In this article, we discuss these variables more comprehensively, alongside the needs within certain kinds of experiments, to assist the Raman spectroscopist in their laser choice.