Artificial Spidroin Bioelectronic Dressing for Smart Wound Management

Abstract

Wound infection has always been a major threat to human health. Most of the existing wound medical materials are made of composite materials with poor biocompatibility and may contain harmful chemicals, which may cause allergic reactions and secondary wound infections, becoming a hidden danger to human health. Therefore, there is an urgent need to develop innovative medical materials for wound treatment. At present, the intelligent application of high-performance materials prepared from artificial spider silk protein (spidroin) for wound healing has been widely studied. Its advantages include good biocompatibility, biodegradability, cell adhesion and excellent bioelectronic performance. In this paper, the biological application of various high-performance medical materials prepared from artificial spidroins for wound healing was introduced, and the sequence design and synthesis methods of artificial spidroins were briefly discussed. Finally, the application prospects of high-performance medical materials prepared from artificial spidroins for wound treatment are discussed.