Heparin Binding Induced Supramolecular Chirality into Self-Assembly of Perylenediimide bolaamphiphile

Abstract

Chirality is one of the hallmark of biomolecules. Here we utilize heparin, a chiral biomolecule and a potent drug, to induce chiral organization into the assembly of achiral molecule. Polyanionic heparin binds with dicationic perylenediimide derivative to induce supramolecular helical organization in aqueous medium as well as in a highly competitive cell culture medium.