Issue 33, 2024, Issue in Progress

Green and efficient synthesis of dibenzyl cyanamides and ureas with cyanamide as a block

Abstract

A method for the two-step synthesis of dibenzyl cyanamide and dibenzyl urea via cyanamide is presented. This approach is both efficient and environmentally friendly. Various N,N-dibenzyl ureas could be obtained by reactions of N,N-dibenzyl cyanamides and N,N-dibenzyl cyanamides as intermediates formed from cyanamide. In the absence of metal, ligand and hydrogen peroxide as the oxidant, products with moderate yields have been obtained under mild conditions. Key features include the use of widely available and easily handled cyanamide sources as starting materials.

Graphical abstract: Green and efficient synthesis of dibenzyl cyanamides and ureas with cyanamide as a block

Supplementary files

Article information

Article type
Paper
Submitted
12 Jun 2024
Accepted
16 Jul 2024
First published
29 Jul 2024
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2024,14, 23693-23698

Green and efficient synthesis of dibenzyl cyanamides and ureas with cyanamide as a block

Z. Wang, Y. He, F. Wang, Y. Wang, H. Luo, J. Wu and J. Yang, RSC Adv., 2024, 14, 23693 DOI: 10.1039/D4RA04286G

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