Metal-free hydrophosphorodithiolation of alkynes with P4S10 and alcohols leading to vinyl phosphorodithioates

Abstract

A simple and metal-free strategy has been developed for the construction of vinyl phosphorodithioates via direct hydrophosphorodithiolation of alkynes with P₄S₁₀ and alcohols. This three-component reaction could be conducted under mild conditions to access a variety of vinyl phosphorodithioates with Z-isomers as the major products without the use of any metal reagents, ligands, or additives. Preliminary mechanistic studies suggested that a radical process was involved in this reaction procedure.