Issue 1, 2025

Paired electrocatalysis enabled oxidative coupling of styrenes with alkyl radicals

Abstract

A paired electrocatalysis strategy for intermolecular oxidative cross-dehydrocoupling between styrenes and ethers or p-methylphenol derivatives using ketone as a mild oxidant is described. This approach enables the generation of Csp3 carbon-centered radicals through anodic oxidation, followed by reductive coupling of ketones at the cathode, ultimately yielding valuable oxidative alkylation products.

Graphical abstract: Paired electrocatalysis enabled oxidative coupling of styrenes with alkyl radicals

Supplementary files

Transparent peer review

To support increased transparency, we offer authors the option to publish the peer review history alongside their article.

View this article’s peer review history

Article information

Article type
Communication
Submitted
04 Oct 2024
Accepted
28 Oct 2024
First published
30 Oct 2024

Org. Biomol. Chem., 2025,23, 78-82

Paired electrocatalysis enabled oxidative coupling of styrenes with alkyl radicals

D. Li, L. Zhang, D. Li, P. Yu and T. Shen, Org. Biomol. Chem., 2025, 23, 78 DOI: 10.1039/D4OB01605J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements